Gotu Kola wepụ 40% Asiaticosides | 16830-15-2

Okwu Mmalite nke Gotu Kola wepụ 40% Asiaticosides:

Centella asiatica, ahịhịa a mịrị amị nke Centella asiatica, ka edebere na mbụ na "Shen Nong's Materia Medica" wee depụta ya dị ka ọkwa etiti.

Ọ nwere mmetụta nke ikpochapụ okpomọkụ na iru mmiri, detoxifying na ibelata ọzịza. Ọgwụgwọ ọnya, ọrịa akpụkpọ, wdg.

Isi ihe na-arụsi ọrụ ike na Centella asiatica wepụ nke a pụrụ iji na ihe ịchọ mma bụ asiatic acid, madecassic acid, madecassoside na madecassoside, madecassoside bụ triterpenoid saponin nke Centella asiatica Ọ bụ otu n'ime ihe ndị na-arụ ọrụ nke nwere oke kachasị elu, na-aza ihe dịka 30% Mkpokọta glycosides nke Centella asiatica.

Ịdị irè na ọrụ nke Gotu Kola wepụ 40% Asiaticosides: 

Antibacterial

Centella asiatica wepụ nwere asiatic acid na madecassolic acid, ndị a na-arụ ọrụ saponins ga acidify na cytoplasm na osisi mkpụrụ ndụ, a antibacterial ọrụ nwere ike ichebe osisi n'onwe ya megide ebu na yist ọgụ, nnwale na-egosi na Centella asiatica.

Mwepụta ahụ nwere mmetụta mgbochi ụfọdụ na Pseudomonas aeruginosa, Staphylococcus aureus na Propionibacterium acnes.

mgbochi mkpali

Centella asiatica mkpokọta glycosides nwere mmetụta mgbochi mkpali doro anya: belata mmepụta nke ndị mgbasa ozi pro-inflammatory (L-1, MMP-1), melite ma rụkwaa ọrụ mgbochi nke anụ ahụ, si otú a na-egbochi ma na-agbazi adịghị arụ ọrụ nke anụ ahụ.

Ọnya na ọnya na-agwọ ọrịa

Madecassoside na madecassoside bụ ihe na-arụsi ọrụ ike nke Centella asiatica na ọgwụgwọ ọnya na-agwọ ọkụ.

Ha nwere ike ịkwalite njikọ nke collagen na angiogenesis n'ime ahụ, kpalie uto granulation na ọrụ ndị ọzọ dị mkpa, n'ihi ya, ha bara uru maka ọgwụgwọ ọnya.

N'otu oge ahụ, asiaticoside nwere mmetụta proliferation na epidermal keratinocytes na vaskụla endothelial mkpụrụ ndụ, na-enwe mmetụta inhibitory na fibroblasts, si otú na-akwalite guzobe granulation anụ ahụ na mmalite ogbo nke ọnya na-agwọ ọrịa, na-egbochi scar e guzobere n'oge ikpeazụ. mmetụta ọgwụgwọ ọnya.

Mgbochi ịka nká

Centella asiatica wepụ nwere ike ịkwalite njikọ nke collagen I na III, yana nzuzo nke mucopolysaccharides (dị ka njikọ nke sodium hyaluronate), na-amụba njigide mmiri nke akpụkpọ ahụ, mee ka ọ rụọ ọrụ ma na-emegharị mkpụrụ ndụ akpụkpọ anụ, mee ka ọ dịkwuo mma, na-eme ka akpụkpọ ahụ dịkwuo mma. kenkowaputa.

N'aka nke ọzọ, nyocha nke usoro DNA chọpụtara na Centella asiatica wepụ na-emekwa ka mkpụrụ ndụ ihe nketa fibroblast rụọ ọrụ, nke nwere ike ime ka mkpụrụ ndụ basal akpụkpọ anụ dịkwuo mma, na-eme ka akpụkpọ ahụ dịkwuo mma na nkwụsi ike, yana ezigbo wrinkles ihu.

Antioxidant

Asiaticoside, madecassoic acid na madecassoic acid niile nwere ihe omume antioxidant doro anya.

Nsonaazụ nke nnwale anụmanụ na-egosi na madecassoside nwere ike ịkpata superoxide dismutase, glutathione na peroxidase na ọnya n'oge mmalite nke ọgwụgwọ ọnya.

Ọkwa nke antioxidants dị ka catalase, VitCHing, VitE abawanyela nke ukwuu, na ọkwa nke lipid peroxides na ọnya belatara ugboro asaa.

Na-acha ọcha

Asiaticoside nwere ike igbochi ọrụ tyrosinase n'ụzọ dabere na dose, yana 4μg/ml asiaticoside na-egbochi tyrosinase site na 4%.