L-Carnitine | 541-15-1

L-carnitine, mgbe ụfọdụ a na-akpọ ya nanị carnitine, bụ ihe na-edozi ahụ nke emepụtara site na amino acid methionine na lysine na imeju na akụrụ ma chekwaa ya na ụbụrụ, obi, anụ ahụ, na spam. Ọtụtụ ndị mmadụ na-emepụta ihe oriri a zuru oke iji nọgide na-adị mma. Ụfọdụ nsogbu ahụike, Otú ọ dị, nwere ike igbochi carnitine biosynthesis ma ọ bụ gbochie nkesa ya na mkpụrụ ndụ anụ ahụ, dị ka nkwụsịtụ oge, ọrịa obi, na ụfọdụ ọrịa mkpụrụ ndụ ihe nketa. Ụfọdụ ọgwụ nwekwara ike imetụta carnitine metabolism n'ime ahụ. Ọrụ bụ isi nke L-carnitine bụ ime ka lipids, ma ọ bụ abụba, ghọọ mmanụ ọkụ maka ike.
Kpọmkwem, ọrụ ya bụ ịkwaga acid fatty n'ime mitochondria nke mkpụrụ ndụ eukaryotic nke bi n'ime mkpuchi nchebe nke gbara sel gburugburu. N'ebe a, acid fatty na-enweta beta oxidation wee gbarie ka ọ bụrụ acetate. Ihe omume a bụ ihe na-amalite usoro Krebs, usoro mmeghachi omume dị mgbagwoju anya nke dị mkpa iji nye ume maka cell ọ bụla n'ime ahụ.L-carnitine na-ekerekwa òkè n'ichekwa njupụta ọkpụkpụ. N'ụzọ dị mwute, ihe oriri a na-aghọ obere ihe na ọkpụkpụ yana osteocalcin, protein nke osteoblasts zoro ezo nke na-etinye aka na nchịkọta ọkpụkpụ. N'ezie, adịghị ike ndị a bụ isi ihe na-eme ka ọkpụkpụ ọkpụkpụ na-eme ka ụmụ nwanyị mechaa menopause. Nnyocha egosiwo na enwere ike gbanwee ọnọdụ a site na mgbakwunye L-carnitine, nke na-abawanye ọkwa osteocalcin dịnụ.
Okwu ndị ọzọ ọgwụgwọ L-carnitine nwere ike lebara anya gụnyere itinye n'ọrụ glucose na-abawanye na ndị ọrịa mamịrị, mbelata mgbaàmà metụtara ọrịa ike ọgwụgwụ na-adịghị ala ala, yana melite ụkpụrụ thyroid na ndị nwere hyperthyroidism. Enwekwara ihe akaebe na-egosi na propionyl-L-carnitine nwere ike inye aka melite arụ ọrụ erectile na ụmụ nwoke, yana ịkwalite irè sidenafil, ọgwụ a na-ere n'okpuru ụghalaahịa Viagra. Na mgbakwunye, nchọpụta egosila na nri a na-eme ka ọnụ ọgụgụ spam na motility dịkwuo mma.