Melittin | 20449-79-0
Nkọwa ngwaahịa:
Melittin bụ nsí peptide nke a na-achọta na nsị aṅụ, karịsịa n'ime nsị nke mmanụ aṅụ (Apis melifera). Ọ bụ otu n'ime ihe ndị bụ isi na-eme nsị anụ ma na-enye aka na mkpali na mmetụta mgbu na-ejikọta ya na nsị aṅụ. Melittin bụ obere peptide linear nke nwere amino acid 26.
Isi njirimara melittin gụnyere:
Ihe owuwu: Melittin nwere usoro amphipathic, nke pụtara na ọ nwere mpaghara hydrophobic (mmiri na-egbochi mmiri) na mpaghara hydrophilic (mmiri na-adọta). Usoro a na-enye ohere ka melittin na-emekọrịta ihe na mebie membranes cell.
Mechanism of Action: Melittin na-arụ ọrụ ya site na imekọrịta ihe na membranes cell. Ọ nwere ike na-etolite pores na lipid bilayer nke cell membranes, na-eduga na ụba permeability. Nke a na-emeghasịkwa mkpụrụ ndụ sel nwere ike ịkpata lysis cell na mwepụta nke ọdịnaya cellular.
Azịza mkparị: Mgbe aṅụ na-agba, a na-agbanye melittin n'ime akpụkpọ anụ onye ahụ yana ihe ndị ọzọ na-egbu egbu. Melittin na-enye aka na mgbu, ọzịza, na ọbara ọbara jikọtara ya na nsị aṅụ site na ịkpalite nzaghachi mkpali.
Njirimara Antimicrobial: Melittin na-egosipụtakwa ihe mgbochi nje. A mụọla ya maka ike ya ịkpaghasị akpụkpọ ahụ nke nje bacteria, nje, na fungi, na-eme ka ọ bụrụ isiokwu nke mmasị maka ngwa ọgwụgwọ nwere ike ime, dị ka ịmepụta ihe ndị na-egbochi nje.
Ngwa ọgwụgwọ enwere ike: N'agbanyeghị ọrụ ọ na-ekere na mgbu na mbufụt nke nsị aṅụ na-akpata, e nyochara melittin maka ọgwụgwọ ya nwere ike ime. Nnyocha enyochala ihe ndị na-egbochi mkpali na mgbochi ọrịa cancer, yana ike ya na usoro nnyefe ọgwụ.
ngwugwu:25KG/Bag ma ọ bụ dị ka ị rịọrọ.
Nchekwa:Chekwaa n'ebe ikuku na-ekpo ọkụ, nke kpọrọ nkụ.
Onye isi ocheỌkọlọtọ:Ọkọlọtọ mba ụwa.