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Topicastat nwere mmetụta mgbochi asọmpi na xanthine oxidoreductase, si otú a na-egbochi mmepụta uric acid. Ọ nweghị mmetụta mgbochi na pyrimidine purine metabolizing enzymes ndị ọzọ, mana na-ahọrọ nke na-egbochi mmetụta akwụkwọ kemịkal na xanthine oxidoreductase. Topicastat nwere mmetụta mgbochi dị ịrịba ama na ma oxidized na mbelata XOR, ya mere mmetụta ya nke iweda uric acid dị ike ma dịgidere, ya mere enwere ike iji ngwaahịa a maka ọgwụgwọ hyperuricemia na-adịghị ala ala na gout.