Hyaluronidase |37326-33-3
Nkọwapụta ngwaahịa:
Hyaluronidase bụ enzyme nke nwere ike hydrolyze hyaluronic acid (hyaluronic acid bụ akụkụ nke anụ ahụ matriks nke nwere mmetụta mgbasa nke ịmachi mmiri na ihe ndị ọzọ extracellular).
Ọ nwere ike belata viscosity nke ihe intercellular nwa oge, na-akwalite infusion subcutaneous, exudate echekwara na mpaghara ma ọ bụ ọbara iji mee ngwangwa mgbasa na ịkwado nnabata, yana ọ bụ onye na-ekesa ọgwụ dị mkpa.
A na-eji ụlọ ọgwụ eme ihe dị ka onye na-emepụta ọgwụ na-akwalite ịṅụ ọgwụ ọjọọ, kwalite edema mpaghara ma ọ bụ hematoma dissipation mgbe ịwachara ahụ na trauma.
| ITEM | SPEC |
| Uru PH | 5.0-8.5 |
| Akụkụ akụkụ | 100% Site na 80 Mesh |
| Nyocha | 98% |
| Ọnwụ na ihicha | ≦5.0% |
| Ihe omume | Ọ bụghị ihe na-erughị 300(400-1000)IU/mg, na ihe a mịrị amị |
| Nfefe ọkụ | T550nm>99.0% |
| Ngụkọta ọnụ ọgụgụ efere | ≤1000cfu/g |
| Mkpokọta yist & ebu | ≤100cfu/g |
| Ọnọdụ nchekwa | 2-8 Celsius C |
Nkọwa ngwaahịa
Nkọwa ngwaahịa:
Ihe na-acha ọcha ma ọ bụ ọkụ na-acha odo odo, nke na-esighị ike, na-agbaze ngwa ngwa na mmiri, nke na-adịghị edozi na ethanol na acetone, yana ezigbo pH nke 4.5-6.0.
Nkwụsi ike: Ngwaahịa a kpochara akpọnwụ enweghị mbelata dị ukwuu na ike ka echekwara ya na 4 ℃ maka otu afọ;
N'okpuru ọnọdụ nke 42 ℃, ọrụ na-anọgide na-agbanwe agbanwe mgbe kpo oku maka 60 nkeji;Kpoo ọkụ na 100 ℃ maka nkeji 5 iji jide 80% ume ike;Ngwọta mmiri dị ala dị ala na-adịkarị mfe nkwụsị, na ịgbakwunye NaCl nwere ike ịbawanye nkwụsi ike ha;Ọ dị mfe ịka njọ mgbe ikpo ọkụ.
Ihe mgbochi gụnyere ion metal dị arọ (Cu2+, HR <2+, Fe <3+ Chemalbook, Mn<2+, Zn <2+), ihe na-esi ísì ụtọ organic acid, bile salts, polyanions, na polysaccharides dị arọ dị elu dị ka Chondroitin sulfate B, heparin, na heparan sulfate.
Onye na-eme ihe bụ polycation.Ọnụ ọgụgụ nke absorption nke 1% mmiri mmiri na 280nm bụ 8. Hyaluronidase tumadi hydrolyzes N-acetyl na hyaluronic acid- β- N'etiti D-glucosamine na D-glucuronic acid β-1,4-bond, na-emepụta tetrasaccharide residues na-enweghị na-ahapụ monosaccharides. mmeghachi omume: hyaluronic acid + H2O oligosaccharides.
Ngwa:
1. Eji ya mee nyocha biochemical
2. N'ụlọ ọgwụ, a na-ejikarị eme ihe iji kwalite mgbasa nke edema mpaghara ma ọ bụ hematoma mgbe ịwachara ahụ na trauma, belata ihe mgbu na ebe a na-agba ọgwụ, ma mee ka mmịnye nke subcutaneous na intramuscular injections.
3. A pụkwara iji ya mee ihe maka eriri afọ.
ngwugwu: 1g, 5g, 10g, 30g, 50g, 100g, 500g, 1kg, 5kg, 10 n'arọ;25kgs/bag ma ọ bụ dị ka ị rịọrọ.
Nchekwa:Chekwaa n'ebe ikuku na-ekuku, nke kpọrọ nkụ.
Standardkpụrụ Executive:Ọkọlọtọ mba ụwa.